samyr

A superb methylation agent for mental andSamyr  Oral (SAMe Oral) [20x400mg Tablets] physical improvement SAMe (S-Adenosyl-L-methionine) is a natural chemical that plays an essential part in energizing chemical processes throughout the body. SAMe is involved in methyl-donor conversion. That is to say that it is used in varied chemical processes throughout the body and consequently has a major role in the production of the ‘energy of life’ molecule, ATP (adenosine triphosphate). There is also a correlation between SAMe and melatonin. When melatonin levels are low SAMe levels are high and vice-versa. SAMe has been described as the day-time alertness hormone, in the same way that melatonin has been described as the night-time sleep hormone. SAMe is the 3rd most concentrated chemical in the liver, so it has been widely used to correct liver disorders such as cirrhosis and even hepatitis. A better liver, means better detoxification, that has an impact on general health and well-being. Also, being natural, SAMe doesn't have any of the serious side effects that are associated with many other liver drug treatments. Due to its energy enhancing action, SAMe has become one of the most sought after anti-depressants in recent times (though its use should be avoided by patients suffering from manic depression). SAMe has even been found to reduce pain and swelling in osteoarthritis sufferers. Dosage: Anti-depressant doses are 800mg to 2000mg daily. Osteoarthritis doses are 400mg to 1200mg daily. Liver disorder doses are 500mg and 1600mg daily. General anti-aging requires about 300mg to 500mg daily. Caution: Keep the tablets cool and out of sunlight, and do not remove the tablets from the blister pack until you are ready to take them. SAMe tablets are enteric coated so they should not be crushed or broken. As in keeping with IAS policy, we only offer a pharmaceutical grade product that is produced and packaged correctly, in order to be effective when you consume it. Avoid the use of SAMe's that are not enteric coated and not protected from light, they will be ineffective. Only use with other anti-depressant drugs with your doctor's guidance. Manufacturer's Insert SAMYR ® QUALITATIVE AND QUANTITATIVE COMPOSITION: One 400-mg bottle of lyophilised powder contains: ademetionine (S-Adenosyl-L-Methionine), 1.4-butanedisulfonate, 760 mg equal to 400 mg. One phial of solvent solution contains: water for injectable solutions, L-lysine, sodium hydroxide. One 400-mg gastro-resistant tablet contains: ademetionine (S-Adenosyl-L-Methionine) 1.4-butanedisulfonate, 760 mg equal to 400 mg. Excipients: Microcrystalline cellulose, magnesium stearate, polyethylene glycol 6000, polymethacrylate, polysorbate, colloidal silica, emulsified silicone, sodium starch glycolate, talc. PHARMACEUTICAL PRESENTATION: 5 400-mg bottles of lyophilised powder + 5 phials of solvent solution 20 400-mg tablets of gastro-resistant tablets PHARMACEUTICAL CATEGORY: Anti-depressant THERAPEUTICAL INDICATION: Symptoms of depression CONTRAINDICATIONS: Known individual hypersensitivity to the product. PRECAUTIONS: The lyophilised powder must be mixed with the accompanying solvent solution immediately prior to use. The intravenous injection should be carried out very slowly. SAMYR tablets are gastro-resistant, thus releasing the ademetionine in the duodenum. The tablets should not be removed from the blister pack until just prior to use. These should not be chewed but swallowed whole. For better absorption of the main principle and a more through therapeutic effect, SAMYR should be taken between meals. INTERACTIONS SAMYR is compatible with any other anti-depressant treatments, particularly tricyclens and monoaminoxidase inhibitors. Taking ademetionine does not cause negative interactions with alcohol. WARNING: Effects on the capacity to drive or use machinery. Does not interfere with the capacity to drive vehicles or to operate machinery. DOSAGE OF, DIRECTIONS FOR AND FREQUENCY OF USE: Ampoules: 1 bottle per day for a 15-20 day cycle, to be taken intravenously or intramuscularly. Tablets: 2-3 tablets per day according to your doctor's prescription. The treatment can be initiated parenterally (one bottle per day intravenously or intramuscularly for 15-20 days) and continued orally (2-3 tablets per day). Overdose: Cases of overdose are practically unknown. ADVERSE EFFECTS: Significant side effects have not been seen, not even over long periods of treatment or with a high dosage. Nor have cases been reported of habit formation or drug-dependence. Ademetionine can be taken safely during pregnancy, by the elderly and by those with chronic hepatic problems. SAMYR has been known to cause rare disturbances in the sleep rhythms of hypersensitive patients. Should this occur, a sleeping medication (hypnotic) might be useful. Given the acid pH, which for stabilising reasons is maintained in the active principle in the tablets, cases have been reported of heartburn and a sense of epigastric heaviness by patients who have taken this product orally. However, such episodes are of short duration and should not warrant stopping the treatment. If at any time the patient should note any adverse effects other than the above he should consult his doctor. EXPIRY: See the expiry date shown on the box. This applies to the product properly stored and packaged. Warning: Do not use this product after the expiry date printed on the box. Keep SAMYR away from sources of heat. Should the lyophilised powder take on a colour other than its original white, owing to breakage of the bottle or exposure to heat, return the product in its entirety to your chemist and have it exchanged. PHIALS WITH SAFETY PRE-OPENING: Instructions for opening - Position the ampoule as shown in figure 1. - Exert pressure with the thumb on the COLOURED DOT as shown in figure 2. If the lot number shown on the box includes the letter "B", the phials of lyophilized material have been manufactured by Boehringer Mannheim Italia Spa in the Monza (Milan) office. If the lot number shown on the box includes the letter "F", the Fidia Spa has manufactured the phials of lyophilized material in the Abano Terme (Padua) office.

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